Vitreous metastases of primary cutaneous B-cell lymphoma.

Vitreous metastases of primary cutaneous B-cell lymphoma.

Ocul Immunol Inflamm. 2009 Sep-Oct

Chong DY, Johnson MW, Shen D, Chan CC, Callanan DG.

Texas Retina Associates, Arlington, TX, USA.

Purpose: To describe two cases of vitreous metastases of primary cutaneous B-cell lymphoma (PCBCL). Methods: Observational case series. Results: A 73-year-old man and an 81-year-old woman, both with a history of PCBCL, diffuse large cell type, presented with decreased visual acuity due to vitritis. Both patients underwent vitreous biopsy that demonstrated B-cell lymphoma, large cell type, and confirmed metastases of cutaneous B-cell lymphoma to the vitreous. Conclusion: PCBCL, diffuse large cell type, is a rare form of non-Hodgkin lymphoma that can metastasize to the vitreous without visible chorioretinal involvement.

PMID: 19831568 [PubMed - in process]

Primary cutaneous B cell lymphoma presenting as recurrent eyelid swelling.

Primary cutaneous B cell lymphoma presenting as recurrent eyelid swelling.
Clin Experiment Ophthalmol. 2008 Oct

Pandya VB, Conway RM, Taylor SF.
University of Sydney, Sydney, NSW, Australia.

Primary cutaneous lymphoma represents a distinct clinical entity within the spectrum of haematological malignancy. A case of primary cutaneous B cell lymphoma is reported, presenting in an 87-year-old female with a 2-year history of intermittent swelling and discolouration of the right upper and lower eyelids, in the absence of systemic symptoms. Histopathological examination of an incision biopsy revealed a lymphoid infiltrate in the dermis with immunophenotypic features of B cell lymphoma. Staging investigations confirmed the absence of systemic disease. Treatment with oral chemotherapy was undertaken with a good response. Ophthalmologists should include primary cutaneous lymphoma in the differential diagnosis of recurrent eyelid swelling.

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