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Monday, August 27, 2012

Radiotherapy in the Management of Localized Primary Cutaneous B-Cell Lymphoma.

Radiotherapy in the Management of Localized Primary Cutaneous B-Cell Lymphoma.

August 2012

Corresponding author: Itai Pashtan, MD, Department of Radiation Oncology
Brigham and Women's Hospital, 75 Francis Street, ASB1-L2, Boston, MA 02115
USA. Tel: +1-617-732-6231; Fax: +1-617-975-0932; E-mail: 

Primary cutaneous B-cell lymphomaprognosisradiationdoselocal control

The optimal therapy and radiation dose for patients with localized primary cutaneous B-cell lymphoma (PCBCL) are unknown. We retrospectively identified 23 patients with localized (T1-T2) PCBCL treated with definitive radiation to doses ranging from 30–44 Gy (median, 36 Gy). With median follow-up of 4.8 years, the 5-year overall survival rate was 100%, the relapse-free survival rate was 71% (95% CI, 46-86%) and there were no local recurrences, suggesting that radiotherapy to a dose of 30 Gy may be sufficient for cure.


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